Christian McCaffrey (calf/Achilles) has been placed on injured reserve, knocking him out for at least the next four weeks. (Adam Schefter on Twitter)

ESPN sources: 49ers officially are placing All-Pro RB Christian McCaffrey on injured reserve due to his calf tightness and Achilles tendinitis. McCaffrey now will miss the next four games, at least, before the team assesses whether he can return in mid-October. pic.twitter.com/VV9GRihDrL

Fantasy Impact:

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